Table 1 Association between the -394 4N del/ins polymorphism of Ddah1 and osteoporosis, analyzed by logistic regression.

From: Mechanical force promotes dimethylarginine dimethylaminohydrolase 1-mediated hydrolysis of the metabolite asymmetric dimethylarginine to enhance bone formation

 

Genotype, n (%)

4N del/ins + ins/ins

Samples (n = 1404)

del/del

del/ins

ins/ins

Frequency

Unadjusted OR

Adjusted OR

    

%

(95% CI)

(95% CI)

Control (n = 470)

378 (80.4)

84 (17.9)

8 (1.7)

19.6

Reference

Osteopenia (n = 635)

464 (73.1)

151 (23.8)

20 (3.1)

26.9

1.45 (1.13–1.86)&

1.42 (1.07–1.88)*

Osteporosis (n = 299)

219 (73.2)

70 (23.4)

10 (3.4)

26.8

1.45 (1.08–1.94)*

1.57 (1.03–2.40)*

  1. Odds ratios (ORs) and 95% confidence intervals (CIs) were obtained by logistic regression, with and without adjustment for sex, age, and body mass index.
  2. *p < 0.05. &p < 0.01. OR, an indicator of the degree of association between exposure and disease, and was analyzed by logistic regression.
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