Fig. 4: lncRNAs during fungal infection of epithelial cells.
From: The long non-coding RNA landscape of Candida yeast pathogens
a lncRNAs expression dynamics plots based on log2 fold changes compared to time point 0. Each line (up-regulated—red, down-regulated—blue) corresponds to the fold change of expression levels of a lncRNA. Numbers on the plots indicate the number of differentially expressed lncRNAs (|log2 fold change | >1.5, padj < 0.01, in red—intergenic lncRNAs, in black—antisense lncRNAs); b Venn diagrams of differentially expressed* (DE*) lncRNAs during infection (in green) and in control samples (in blue). *To identify infection-specific genes with a higher stringency, we applied filters of |log2 fold change | >0 and padj < 0.01 to the DE lncRNA sets in both conditions in order to maximize the overlap between them, hence ensuring that lncRNAs in control samples even with small fold-changes are discarded. The numbers of “infection-specific” lncRNAs are indicated in green-only portions of Venn diagrams.
