Fig. 3: Co-housing promoted gallstone formation in gallstone-resistant mice. | Nature Communications

Fig. 3: Co-housing promoted gallstone formation in gallstone-resistant mice.

From: Gut microbiota promotes cholesterol gallstone formation by modulating bile acid composition and biliary cholesterol secretion

Fig. 3

A Left: a schematic show of the process of co-housing experiment. Right: incidence of gallstone in each group of mice (n = 10 mice/group). B Principal coordinate analysis of gut microbiota in cecum contents from each group of mice. C Biliary lipid composition and cholesterol saturation index (CSI) of gallbladder bile in each group (n = 5 mice/group). Data are expressed as mean ± SEM. Statistics was performed by two-sided ANOVA with LSD post hoc analysis between groups. D Abundance of gut microbiota at the order level in each group (n = 5 mice/group). “C”: C57BL/6J, “A”: AKR/J, “coH.C”: C57BL/6J co-housing with AKR/J and “coH.A”: AKR/J co-housing with C57BL/6J. Source data are provided as a Source data file.

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