Fig. 2: Nanobody binding sites of the 1918 polymerase determined by cryo-EM and X-ray crystallography.
From: Mapping inhibitory sites on the RNA polymerase of the 1918 pandemic influenza virus using nanobodies

a Composite model showing the binding position of each nanobody on the surface of the 1918 polymerase determined using cryo-EM. C-terminal domain of PA, PA-C; N-terminal one third of PB2, PB2-N. b–d Crystal structures of PB2 cap-mid-link and nanobody complexes.