Fig. 1: Chiral aryl-fused azabicyclo[3.3.1]nonane compounds and their synthesis. | Nature Communications

Fig. 1: Chiral aryl-fused azabicyclo[3.3.1]nonane compounds and their synthesis.

From: Asymmetric synthesis of N-bridged [3.3.1] ring systems by phosphonium salt/Lewis acid relay catalysis

Fig. 1

a Representative bioactive molecules containing aryl-fused azabicyclo[3.3.1]nonane framework. b Reported total synthesis strategies for preparing chiral azabicyclo[3.3.1]nonane scaffolds. c The first catalytic asymmetric approach to construct azabicyclo[3.3.1]nonane molecules by metal-free relay catalysis (this work).

Back to article page