Fig. 5: Cascade radical 4-exo-dig/7-endo-trig cyclization to bicyclic azetidine 2aj.
Reaction conditions: ynamide 1aj (0.2 mmol), [Cu(bcp)DPEphos]PF6 (5 mol%), (i-Pr)2NEt (2 mmol), MeCN (0.1 M), r.t., 16 h. Isolated yield is provided.
Fig. 5: Cascade radical 4-exo-dig/7-endo-trig cyclization to bicyclic azetidine 2aj. | Nature Communications
