Fig. 2: Cryo-EM structure of Arpin_CA bound to Arp2/3 complex.
From: Molecular mechanism of Arp2/3 complex inhibition by Arpin
a Cryo-EM map of Arpin_CA bound to Arp2/3 complex colored by resolution (as indicated by the side bar). Labels indicate the approximate location of Arp2/3 complex subunits. b Representative region of the 3.24-Å resolution cryo-EM map, showing the definition of side chains for the α-helix formed by residues Y253-A268 of ArpC2. c Cryo-EM map of Arpin_CA (marine blue) bound to Arp2/3 complex. Arp2/3 complex subunits are labeled and colored as follows: Arp2, cyan; Arp3, green; ArpC1, yellow; ArpC2, gray; ArpC3, blue-white; ArpC4, blue-white; ArpC5, gray. The Arpin_CA density appears as two separate patches shown in insets and corresponding to the C-helix and A domain.
