Fig. 6: Summary of Cas9-induced variants at on- and off-target sites. | Nature Communications

Fig. 6: Summary of Cas9-induced variants at on- and off-target sites.

From: CRISPR-Cas9 induces large structural variants at on-target and off-target sites in vivo that segregate across generations

Fig. 6

The frequencies of Cas9-induced variants in all analyzed samples for the F0 and F1 generations are displayed in the summary plots (a–d). Each point represents one sample (i.e., a pool of larvae or an individual juvenile/adult fish). a The total frequencies of Cas9-induced variants at on-target sites. b The frequencies of SVs induced by Cas9 at on-target sites. c The total frequencies of Cas9-induced variants at off-target sites (sh2b3 off-target 1, ywhaqa off-targets 1 and 2). d The frequencies of SVs induced by Cas9 at off-target sites. Source data are provided as a Source Data file.

Back to article page