Fig. 3: Major interactions stabilizing ICD structures.
From: Structures of highly flexible intracellular domain of human α7 nicotinic acetylcholine receptor
a Uneven distribution of charge residues (blue: ARG and LYS; red: GLU and ASP) in the ICD. b–d Representative electrostatic interactions that stabilize tertiary structure (yellow), and quaternary structure (yellow–orange). e Representative hydrogen bonding in disordered loop regions. f Representative hydrogen bonding between adjacent subunits. g Representative hydrophobic interactions in the ICD. All dash lines in (c) and (d) < 3.2 Å.
