Fig. 5: Validation in a clinical in-house cohort. | Nature Communications

Fig. 5: Validation in a clinical in-house cohort.

From: Machine learning-based integration develops an immune-derived lncRNA signature for improving outcomes in colorectal cancer

Fig. 5

A, B Kaplan–Meier curves of OS (log-rank test: P = 1.93e−9) (A) and RFS (log-rank test: P = 5.23e−5) (B) according to the IRLS. C, D Multivariable Cox regression analysis of OS (C) and RFS (D) in our cohort (n = 232). Statistic test: two-sided Wald test. Data are presented as hazard ratio (HR) ± 95% confidence interval [CI]. E Time-dependent ROC analysis for predicting OS at 1, 3, and 5 years. F The performance of IRLS was compared with other clinical and molecular variables in predicting prognosis in our cohort (n = 232). Statistic tests: two-sided z-score test. Data are presented as mean ± 95% CI. **P < 0.01; ***P < 0.001; ****P < 0.0001.

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