Table 2 Multivariable analysis of the Yonsei cohort.

From: Development and validation of a prognostic and predictive 32-gene signature for gastric cancer

Characteristics

Hazard ratio (95% CI)

P valuea

Age

 ≤60 years

Reference

 

 >60 years

1.95 (1.51, 2.51)

<0.001

Stage

 I

Reference

 

 II

1.86 (0.66, 5.25)

0.241

 III

3.58 (1.31, 9.75)

0.013

 IV

18.2 (6.08, 54.5)

<0.001

Tumor location

 Antrum

Reference

 

 Body

1.02 (0.78, 1.34)

0.871

 Cardia

0.90 (0.56, 1.45)

0.671

 Whole

1.49 (0.60, 3.72)

0.395

Lauren type

 Diffuse

Reference

 

 Intestinal

0.89 (0.65, 1.22)

0.481

 Mixed

0.71 (0.35, 1.42)

0.332

 Other

1.20 (0.86, 1.68)

0.294

Perineural invasion

 Negative

Reference

 

 Positive

1.12 (0.81, 1.55)

0.491

Molecular subtype

 Group 1

Reference

 

 Group 2

1.97 (1.31, 2.95)

0.001

 Group 3

1.73 (1.12, 2.65)

0.013

 Group 4

2.18 (1.44, 3.31)

<0.001

  1. aP value for the interaction term is based on the Cox proportional hazards model.