Table 6 Univariate and multivariate covariate-specific HR for surgery vs. radiation for stage I NSCLC.

From: Uncovering interpretable potential confounders in electronic medical records

 

Univariate analysis

Multivariate analysis

Covariates

HR

95% CI

P value

HR

95% CI

P value

W.surgery

0.309

[0.24, 0.4]

<0.001

0.545

[0.41, 0.72]

<0.001

struct:pat_age

52.9

[17, 1.6e+02]

<0.001

14.6

[4.8, 44]

<0.001

struct:male

3.07

[1.8, 5.1]

<0.001

1.92

[1.1, 3.4]

0.023

struct:race_white

0.842

[0.53, 1.4]

0.476

0.495

[0.28, 0.87]

0.015

struct:race_api

0.0557

[0.019, 0.17]

<0.001

0.0674

[0.021, 0.22]

<0.001

struct:race_black

2.03

[0.62, 6.7]

0.245

1.87

[0.57, 6.1]

0.298

struct:hispanic

0.664

[0.19, 2.3]

0.514

0.331

[0.088, 1.2]

0.101

struct:diagnosis_year

0.0166

[0.007, 0.039]

<0.001

0.0421

[0.014, 0.13]

<0.001

text:alert

9.46e-12

[3.6e-16, 2.5e-07]

<0.001

0.00224

[3e-08, 1.7e+02]

0.287

text:alk

1.17e+04

[38, 3.7e+06]

0.001

4.67e+04

[9.3e+02, 2.3e+06]

<0.001

text:appearance

5.46e-09

[2.6e-12, 1.1e-05]

<0.001

0.00694

[7.6e-06, 6.4]

0.153

text:attention

1.03e-12

[4.6e-20, 2.3e-05]

0.001

0.00238

[1.2e-09, 4.7e+03]

0.414

text:feel

6.64e-10

[5.7e-16, 0.00077]

0.003

1.27e-05

[1.2e-10, 1.4]

0.057

text:left.low

29.1

[5.2, 1.6e+02]

<0.001

12.5

[2.1, 76]

0.006

text:nipple

2.57e-09

[1.6e-15, 0.0041]

0.007

4.2e-05

[1.5e-09, 1.2]

0.054

text:rib

688

[40, 1.2e+04]

<0.001

28.1

[1.8, 4.4e+02]

0.017

text:severe

601

[56, 6.5e+03]

<0.001

58.3

[9.4, 3.6e+02]

<0.001

text:sponge

2.04e-07

[3.3e-11, 0.0013]

<0.001

0.0181

[3.7e-05, 8.9]

0.205

text:squamous.cell

94.8

[16, 5.6e+02]

<0.001

7.61

[1.1, 53]

0.041

text:venous

0.0464

[0.00089, 2.4]

0.128

0.0523

[0.00081, 3.4]

0.165

  1. HR hazard ratio, CI confidence interval, * intersection terms.
  2. The * denotes intersection terms identified by our method. The lower block of covariates represents terms extracted from clinical notes. For each covariate, we show the effect size (HR), the 95% confidence interval (CI), and the statistical significance (P value) from a Wald statistics test.
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