Fig. 2: Conserved Gi-coupling mode for FPR1 and FPR2. | Nature Communications

Fig. 2: Conserved Gi-coupling mode for FPR1 and FPR2.

From: Molecular recognition of formylpeptides and diverse agonists by the formylpeptide receptors FPR1 and FPR2

Fig. 2

a Structural superimposition of the FPR1- and FPR2-Gi complexes based on the alignment of FPR1 and FPR2. The lower panel shows the structural alignment of the cytoplasmic regions of FPR1 and FPR2 in four structures. b, c Detailed interactions between the two FPRs and Gi viewed from two angles. FPR1 and FPR2 are colored in slate and blue, respectively. Gαi, Gβ, and Gγ are colored in cyan, sand, and light blue, respectively. Hydrogen bonds are shown as black dashed lines.

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