Fig. 6: Synergy between different antibody pairs is mediated through lateral heterotypic interactions.
From: Heterotypic interactions drive antibody synergy against a malaria vaccine candidate

Crystal structure of CyRPA (blue) bound to Fab fragments of Cy.003 (yellow), Cy.004 (pink), and Cy.007 (light blue). The lower panels show close-up views of each of the interfaces between Cy.004 and Cy.007 (left), Cy.003 and Cy.007 (centre), and Cy.004 and Cy.003 (right). The residues forming heterotypic interactions are labelled and bonds are indicated with yellow dashed lines.