Fig. 2: Defects of implantation and decidualization in mice with endometriosis.
From: Loss of MIG-6 results in endometrial progesterone resistance via ERBB2
a Experimental design to investigate endometriosis-related infertility. b Average number and uterine images of implantation sites at GD 7.5 in mice with endometriosis (Eosis) on 1 and 3 months after endometriosis induction (n = 6 for sham and n = 8 for endometriosis at 1 month and n = 5 for sham and for n = 11 endometriosis at 3 months). Data are represented as mean ± SEM, ** p = 0.0021 by Ordinary one-way ANOVA test. Scale bars: 1 cm. c Average ratio of stimulated uterine weight to control weight and uterine images of mice with endometriosis after artificially induced decidualization (n = 5 for wild type, n = 7 for sham, and n = 5 for endometriosis at 1 month and n = 6 for wild type, n = 5 for sham, and n = 16 for endometriosis at 3 months). Data are represented as mean ± SEM, *** p = 0.0001 by Ordinary one-way ANOVA test. Scale bars: 1 cm. Three independent experiments were performed for (b) and (c) with similar results. Source data are provided in the Source Data file.
