Fig. 8: Braided cervical cerclage material is associated with immune activation and higher rates of preterm labour.
From: Microbial-driven preterm labour involves crosstalk between the innate and adaptive immune response
Cervicovaginal immune mediators were analysed from women pre- and post-cervical cerclage. The type of material was known for 39 women, 14 women received braided cerclage, and 25 women received monofilament. The fold change concentration of mediators of microbial recognition (a), complement proteins (b), and cytokine concentrations (c) between samples pre-cerclage and post-cerclage are compared between women who had braided cerclage (n = 14) and women who had monofilament cerclage (n = 25). The percentage of women who delivered preterm with a braided cerclage was compared with the percentage who delivered preterm following a monofilament cerclage (d). Statistical analysis was performed using a one-sided Mann–Whitney test and one-sided Fisher’s exact test. Data are presented as mean and standard deviation. Source data are provided as a Source Data file.
