Fig. 5: Gene synteny of type I to IV IFNs. | Nature Communications

Fig. 5: Gene synteny of type I to IV IFNs.

From: Identification and establishment of type IV interferon and the characterization of interferon-υ including its class II cytokine receptors IFN-υR1 and IL-10R2

Fig. 5

Gene synteny of IFNU (a), type I (b), II (c) and III IFN (d) loci in vertebrates. All genes are indicated with arrow symbols which point to the transcription direction. IFNU, type I, II and III IFNs are dyed using red, blue, yellow and green, respectively. The conserved and non-conserved neighbor genes are illustrated in gray and white, respectively. Evolutionary topology is supported by a recent study35. ♯ indicating no reports on type III IFN in elephant shark, but in catshark8, and ♯♯ chicken type III IFN locus which belongs to the conserved “IFNLB loci” in reptile and bird34.

Back to article page