Fig. 6: False positive rate analysis with the synthetic datasets. | Nature Communications

Fig. 6: False positive rate analysis with the synthetic datasets.

From: Rescuing low frequency variants within intra-host viral populations directly from Oxford Nanopore sequencing data

Fig. 6

A The bar plot with x-axis on the left shows the total number of variant calls in the synthetic dataset before and after applying Variabel. The line with x-axis on the right shows the false positive rate at each minimum coverage setting. The variant calls are pre-filtered with 4 different minimum coverage settings (y-axis) before applying Variabel. B The stacked bar plot showing the number of unique variants removed by different filters of Variabel. The variants removed by the low-entropy filter are shown in green, and the variants removed by the AF variation filter are shown in orange. The remaining false positive calls are shown in blue. For both A and B, source data are provided as a Source Data file.

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