Fig. 7: The YΦ motif is strictly conserved in the eukaryotic, monovalent activator PA200.
From: The YΦ motif defines the structure-activity relationships of human 20S proteasome activators
a–e WebLogo (http://weblogo.berkeley.edu) (48) representation of the last six residues of (a) PA200 (n = 7), (b) Rpt5 (n = 9), (c) Rpt3 (n = 9), (d) Rpt2 (n = 9), and (e) PAN (n = 41). Amino acid residues at the P1, P2, P3, and P4 (Y only) positions are colored according to sequence preferences of the HbYX (orange) or nYΦn (blue) motifs. Unspecified, along with P5 and P6 residues are in gray. The height of each residue represents the relative frequency. The complete entry list in Supplementary Table 4.
