Fig. 3: Success as an invader is dependent on strain background, pCF10, and PrgB.

The invasion index (II) is defined as the cell number of the invading strain divided by the cell number of the resident strain in feces (the same primary data used to generate Figs. 1 and 2), at either day 1 or Day 21. Statistical analysis was performed by ANOVA, followed by tests for normal distribution and Mann–Whitney ranked test two-tailed for pair-wise comparison. P values for the population differences between the time points are as follows (invader/resident): ES:pCF10/Sp- <0.001, ES/SpΔprgB- 0.001, ES/Sp- 0.004, ES/Sp:pCF10- <0.001, Sp:pCF10/ES- <0.0001, SpΔprgB/ES- 0.181, Sp/ES- 0.004, Sp/ES:pCF10- 0.505. Detailed statistical analysis is presented in the Source Data File.