Fig. 9: Proposed model of CEP128 modulation of male reproduction.
From: CEP128 is involved in spermatogenesis in humans and mice

The imbalance observed in CEP128 levels included increased CEP128 abundance or loss of CEP128 protein, which suppressed the normal functioning of genes/proteins essential for sperm production and morphology as well as fertilizing capability. Normal sperm eventually failed to form, impairing typical reproductive function.