Table 3 Single proteins that can be targeted by peptides based on references18,19 and are expressed on the cell surface75.

From: The landscape of receptor-mediated precision cancer combination therapy via a single-cell perspective

Protein

Gene symbol

Protein

Gene symbol

APN/CD13

ANPEP

GPC3

GPC3

APP

APP

IL-10RA

IL10RA

PD-L1

CD274

IL-11Rα

IL11RA

CD44

CD44

IL-13Rα2

IL13RA2

P32/gC1qR

CD93

IL-6Rα

IL6R

E-cadherin

CDH1

GP130

IL6ST

N-cadherin

CDH2

VEGFR2

KDR

CD21

CR2

MUC18

MCAM

EGFR

EGFR

Met

MET

Epha2

EPHA2

MMP9

MMP9

EphB4

EPHB4

Thomsen-Friedenreich carbohydrate antigen

MUC1

HER2

ERBB2

NRP-1

NRP1

FGFR1

FGFR1

PDGFRβ

PDGFRB

FGFR2

FGFR2

CD133

PROM1

FGFR3

FGFR3

PTPRJ

PTPRJ

FGFR4

FGFR4

HSPG

SDC2

VEGFR1

FLT1

E-selectin

SELE

VEGFR3

FLT4

Tie2

TEK

PSMA

FOLH1

VPAC1

VIPR1

  1. For easier correspondence with the gene expression data, the entries are listed in alphabetical order by gene symbol. The protein/gene in the two leftmost columns go together as do the protein/gene in the two rightmost columns. In this table, we follow the clinical genetics formatting convention that proteins are in Roman and gene symbols are in italics.