Fig. 4: Immune-oncological proteins and their relationship with West-African ancestry.
From: Serum proteomics links suppression of tumor immunity to ancestry and lethal prostate cancer
a Variance analysis for the levels of each of the 82 immune-oncological cytokines assessed as a function of genetic estimation of West African admixture among men without prostate cancer within the NCI-Maryland study (n = 795). The blue plot represents the proportion of variance that can be explained by the degree of West-African admixture while the grey plot represents the residual variance that remains to be explained by factors other than West-African ancestry. b The median levels of the top six West-African ancestry-correlated immune-oncological proteins were compared between Ghanaian (n = 654), AA (n = 374), and EA (n = 454) men. Error bars represent inter quartile range (IQR). Linearized protein abundances (2^NPX) were used to determine median and IQR for each of the proteins. Data are presented as median ± IQR. Source data are provided as a Source Data file.
