Fig. 4: Example pathway expansion showcase for the biosynthesis of the natural product staurosporine. | Nature Communications

Fig. 4: Example pathway expansion showcase for the biosynthesis of the natural product staurosporine.

From: Expanding biochemical knowledge and illuminating metabolic dark matter with ATLASx

Fig. 4

a Visual representation of the biosynthesis pathway from tryptophan to staurosporine (obtained from KEGG, steps numbered in bold black) has been expanded for one generation around the native intermediates. b The molecular structure of staurosporine. c Network of potential staurosporine biochemistry expanded four generations around the target compound. The size of each compound nodes decreases with each generation. When no compound is indicated, the LCSB compound ID is provided.

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