Fig. 4: Interactions between PoxtA and the ribosome-P-tRNA complex.
From: Structural basis for PoxtA-mediated resistance to phenicol and oxazolidinone antibiotics
a Overview of PoxtA interactions with the 23S rRNA (grey), 16S rRNA h41 (yellow), uL1 (gold), uS7 (green), uL5 (pink), bL33 (tan) and the P-tRNA (light blue). The P-tRNA CCA 3ʹ end, acceptor stem (Acc.), and elbow are indicated. b–e Interactions between the P-tRNA elbow (light blue) and the PoxtA NBD2 (b), the P-tRNA acceptor stem (light blue) and the PoxtA ARD (c), the ARD and the P-tRNA CCA-end, including a modelled water molecule (labelled W) (d, e). f An interaction between the PoxtA ARD α2 and the 23S rRNA. The high-resolution model from the combined 70S volume was used.
