Fig. 3: Visualization of H2S in HCT116 cells. | Nature Communications

Fig. 3: Visualization of H2S in HCT116 cells.

From: A hydrogen sulphide-responsive and depleting nanoplatform for cancer photodynamic therapy

Fig. 3

a Confocal fluorescence images and b quantitative fluorescence intensity of HCT116 cells. c Photoacoustic images and d ratiometric photoacoustic signals (PAS680/PAS900) of H2S in HCT116 cells. Cells were treated with PBS buffer, ZnCl2 (40 μg/mL, 10 min), NaHS (1 mM, 1 h), L-Cys (24 μg/mL, 1 h), PAG (50 μg/mL, 0.5 h) + L-Cys (24 μg/mL, 1 h), LPS (1 μg/mL, 6 h) + L-Cys (24 μg/mL, 1 h), or PAG (50 μg/mL, 0.5 h) + LPS (1 μg/mL, 6 h) + L-Cys (24 μg/mL, 1 h). Data are presented as mean ± s.d. (n = 3). Statistical differences were analyzed by Student’s two-sided t-test. Source data are provided as a Source Data file.

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