Table 1 Comparison of various features of HYPER with existing methods.

From: Group testing via hypergraph factorization applied to COVID-19

  

Plate-based arrays9

   
 

HYPER

8 × 12

16 × 24

P-BEST8

Random assignment11

Double-pooling63

# individuals per batch (n)

Any

96

384

384

Any

Multiple of m/2

# pools (m)

Variable

20

40

48

Any

Even

# splits (q)

≤ 3

2

6

Any

2

# stages

Two

Two

One

Two

Two

Max. balanced pools

✓

×

✓

× w.h.p.a

✓

Max. balanced combinations

✓

✓

✓

× w.h.p.a

× w.h.p.a

Simple to implement by hand

✓

✓

×

✓

✓

Flexible/easily adapted

✓

×

×

✓

✓

Simple to decode by hand

✓

✓

×

✓

✓

Corrects false positive

✓

✓

✓

✓

✓

Corrects false negatives

Optional

×

✓

Optional

×

  1. aWith high probability, i.e., probability of failure ≫ 0.
  2. In contrast to the existing methods, HYPER is simple to implement, flexible to adapt, and maximally balanced.