Fig. 5: UBL3 is required for normal thymic T_reg development.

Quantification of a Foxp3⁺CD25⁺ T_reg or b Foxp3⁻CD25⁺GITR⁺ T_reg precursor frequencies in thymus. Representative plots are shown on the left. Graphs on the right show pooled data from a n = 12 mice examined over four experiments and b n = 9 mice examined over three experiments, with each symbol representing an individual mouse and bars designating mean ± SD. P values shown above bars, one-way ANOVA with Bonferroni’s multiple comparisons test.