Fig. 3: Functional analysis of CRP based on functional annotation and MAGMA gene-property analysis.
From: Genetic analysis of over half a million people characterises C-reactive protein loci
a Functional annotation of the variants in the genomic risk loci of the CRP meta-analysis by ANNOVAR plotted by the proportion of annotated SNPs (independent significant). b MAGMA gene-property analysis results are shown for average expression of 30 general tissue types, the red line indicates the Bonferroni threshold (p = 1.67 × 10−3). c MAGMA gene-set analysis plot of the Bonferroni significant (p < 3.23 × 10−6) gene-sets.
