Table 1 Key resources table.
Reagent or resource | Source | Identifier |
|---|---|---|
Antibodies | ||
    KEAP1 | Santa Cruz Biotechnology | Cat# sc-365626 |
    Vinculin | Sigma | Cat# V4505 |
    SLC7A11 | Cell Signaling Technology | Cat# 12691 S |
    GPX4 | R&D Systems | Cat# MAB5457 |
    FSP1 | Proteintech | Cat# 20886-1-AP |
    NRF2 | Cell Signaling Technology | Cat# 12721 S |
    COQ2 | Santa Cruz Biotechnology | Cat# sc-517107 |
    DHODH | Proteintech | Cat# 14877-1-AP |
    anti-Ki-67 (D2H10) | Cell Signaling Technology | Cat# 9027 |
    anti-4-HNE | Abcam | Cat# ab46545 |
    anti-Phospho-Histone H2A.X (Ser139) | EMD Millipore | Cat# 05–636 |
    anti-Cleaved Caspase-3 | Cell Signaling Technology | Cat# 9661 |
Biological Samples | ||
    PDX TC494 | University of Texas MD Anderson Cancer Center | N/A |
Chemicals, Peptides, and Recombinant Proteins | ||
    RSL3 | Cayman Chemical | Cat# 19288 |
    ML162 | Cayman Chemical | Cat# 20455 |
    FIN56 | Selleck | Cat# S8254 |
    4-CBA (4-chlorobenzoic acid) | Sigma | Cat# 135585 |
    iFSP1 | Cayman Chemical | Cat# 29483 |
    TBHQ | Selleck | Cat# S4990 |
    Apigenin | Cayman | Cat# 10010275 |
    SFN | Selleck | Cat# S5771 |
    Corn oil | Sigma | Cat# 8001-30-7 |
    Erastin | Selleck | Cat# S7247 |
    Ferrostatin | Sigma | Cat# SML0583 |
    BODIPYTM 581/591 C11 | ThermoFischer | Cat# D3861 |
    Propidium Iodide | Roche | Cat# 11348639001 |
    RPMI-1640 | Sigma | Cat# R8758 |
    Penicillin-Streptomycin | Life Technologies | Cat# 15140-122 |
    DMEM | Sigma | Cat# D6429 |
    DPBS | Sigma | Cat# D8537 |
Critical Commercial Assays | ||
    cDNA Reverse Transcription Kit | Applied Biosystems | Cat# 43-688-14 |
    QuantiTect SYBR Green PCR Kit | Qiagen | Cat# 204143 |
    TaqMan™ Universal PCR Master Mix | Applied Biosystems | Cat# 4305719 |
    CCK8 | Dojindo | Cat# CK0413 |
Experimental Models: Cell Lines | ||
    H1299 | Laboratory of Bingliang Fang | N/A |
    H23 | Laboratory of Bingliang Fang | N/A |
    H1703 | Laboratory of Bingliang Fang | N/A |
    H2126 | ATCC | Cat# CRL-5925 |
    H460 | Laboratory of Bingliang Fang | N/A |
    A549 | ATCC | Cat# CRL-7909 |
    HEK-293T | ATCC | CRL-11268 |
Experimental Models: Organisms/Strains | ||
    Mouse: athymic nude mice (female, 4-6 weeks old) | Experimental Radiation Oncology Breeding Core Facility at MD Anderson Cancer Center | N/A |
    Mouse: NOD SCID Gamma (NSG) mice (female, 4-6 weeks old) | Experimental Radiation Oncology Breeding Core Facility at MD Anderson Cancer Center | N/A |
Software and Algorithms | ||
    GraphPad | GraphPad | GraphPad |
    Cancer Dependency Map Portal | Cancer Dependency Map Portal | Cancer Dependency Map Portal |
    FlowJo | FlowJo | FlowJo |
    BD Accuri C6 Plus | BD Accuri C6 Plus | BD Accuri C6 Plus |
    UCSC Xena | UCSC Xena | UCSC Xena |
