Fig. 8: The species and metabolic evolution model of Araliaceae. | Nature Communications

Fig. 8: The species and metabolic evolution model of Araliaceae.

From: Deletion and tandem duplications of biosynthetic genes drive the diversity of triterpenoids in Aralia elata

Fig. 8

a Schematic diagram of divergence times in Apiales. The black points indicate the divergence-time nodes. b The pink and blue boxes represent the metabolites of Panax and A. elata, respectively. Genes involved in the alaroside biosynthetic pathway. The black arrow shows the cyclization of 2,3-oxidosqualene to β-amyrin catalyzed by BAS, the purple arrow shows the hydroxylation at the corresponding site catalyzed by P450, the blue arrow shows the glucuronosylation at the corresponding site by CSL, and the green arrows show the glycosylation reactions by the corresponding UGTs. The blank arrows indicate the pseudogenes in the tandem repeat that are not involved in the alaroside biosynthetic pathway. The compounds in dashed boxes represent the specific triterpenoids in Panax and A. elata. TTs tetracyclic triterpenoids, PTs pentacyclic triterpenoids.

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