Fig. 2: Genomic stability in the non-neoplastic crypts in LS patients.
From: Mutational landscape of normal epithelial cells in Lynch Syndrome patients
a Distribution of non-neoplastic crypts with driver mutations and copy number or structural variants. b Driver mutations in non-neoplastic crypts. Asterisks denote frameshift mutations at microsatellite regions (repeat length ≥ 5). c Copy number variants and structural variants in non-neoplastic crypts. Cn-LOH: copy number neutral loss of heterozygosity. d Percentage of non-neoplastic crypts with copy number or structural variants in each LS patient.
