Fig. 1: Darobactin and its BGC. | Nature Communications

Fig. 1: Darobactin and its BGC.

From: Radical SAM-dependent ether crosslink in daropeptide biosynthesis

Fig. 1

a The chemical structure of darobactin. The key C–O–C and C–C crosslinks that consist the unique bicyclic scaffold of darobactin are highlighted in blue. b The darobactin BGC from Photorhabdus khanii HGB1456 encodes a precursor peptide DarApk, an rSAM enzyme DarEpk, and three ABC transports DarBCDpk. The core sequence of DarApk (DarApk(49-55)) is shown in bold.

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