Fig. 1: Transition-metal-catalyzed asymmetric Csp2–Csp3 cross-coupling reactions.
a Enantioselective Csp2–Csp3 cross-coupling of Csp2–I (Br, Cl) Bonds. b C–F bond Activation by Nu-M Insertion/β-fluorine elimination. c This work: C–F bond activation by Pd-H insertion/allylic defluorination for Csp2–Csp3 cross-coupling.
