Fig. 3: Representative examples for three-component coupling reactions. | Nature Communications

Fig. 3: Representative examples for three-component coupling reactions.

From: Decarboxylative tandem C-N coupling with nitroarenes via SH2 mechanism

Fig. 3

Isolated yield (main products: 49–63; by-products: 49a–63a, 49b–63b) after chromatography were shown in turn. Reaction conditions: 4CzIPN (1 mol%), FeI2 (10 mol%), L1 (10 mol%), carboxylic acid A (0.3 mmol), carboxylic acid B (0.3 mmol), nitroarenes (0.2 mmol), 2,6-lutidine (3.0 equiv.), (EtO)3SiH (2.0 equiv.), MeCN (2 mL), Blue LEDs, 65 °C, 24 h. aReaction time = 32 h.

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