Fig. 4: Breakpoints shared in clonal integration events and HPV integration-related inter-chromosomal translocations. | Nature Communications

Fig. 4: Breakpoints shared in clonal integration events and HPV integration-related inter-chromosomal translocations.

From: Long-read sequencing unveils high-resolution HPV integration and its oncogenic progression in cervical cancer

Fig. 4

a–c Schematic illustrations of authentic chimeric reads representing clonal integration events that participated in the use of shared breakpoints: a ZLR-08, b ZLR-11, and c ZLR-12. The orange box represents the virus genome; the blue and green boxes represent different chromosomes of the human genome. Identical breakpoints were designated by the same number and were linked by dashed lines. Clonal integration events in ZLR-11 and ZLR-12 induced translocations between chromosomes. Source data are provided as a Source Data file.

Back to article page