Fig. 1: Design of hydrolytically degradable, thermosensitive vinyl copolymers. | Nature Communications

Fig. 1: Design of hydrolytically degradable, thermosensitive vinyl copolymers.

From: Vinyl copolymers with faster hydrolytic degradation than aliphatic polyesters and tunable upper critical solution temperatures

Fig. 1

Synthesis of well-defined poly(acrylamide-co-cyclic ketene acetal) (P(AAm-co-CKA)) copolymers by reversible addition−fragmentation chain transfer (RAFT) copolymerization between AAm and CKAs, that exhibit tunable and biologically relevant upper critical solution temperature (UCST), and faster hydrolytic degradation than polylactide (PLA) and poly(lactic-co-glycolic acid) (PLGA).

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