Fig. 8: MYC disrupts transcriptional pause release at androgen receptor targets.

a RNA Pol II traveling ratio reveals greater promoter-proximal pausing at Androgen_response genes (two-tailed t-test). b Graphical summary. TSS: transcription start site; TES: transcription end site; BCR: biochemical recurrence; CRPC: castration resistant prostate cancer; FHRE: forkhead response elements; ARE: androgen response elements.