Fig. 3: Mechanical stress activates the extremely strong FnBPB-loricrin interaction.

Left: dynamic force spectroscopy plot of rupture force vs loading rate (nâ=â2305 curves from six cells). The dotted lines show the extrapolated Bell-Evans fit through the most probable (mean) rupture forces and loading rates for four log-equispaced loading rate bins shown as solid circles. Error bars are the standard deviations. Right: corresponding histograms and Gaussian fits of the data.