Fig. 1: Overview of C(sp3)–C(sp3) bond formation.
From: Copper-catalysed asymmetric reductive cross-coupling of prochiral alkenes

a Asymmetric induction of the new C(sp3)–C(sp3) bond at both carbons. b Prior works (radical involved). c Copper-catalysed conjugate addition of chiral alkyl nucleophiles with α-heterofunctionality. d Copper-catalysed reductive coupling of two conjugate alkenes (this work).