Fig. 2: A variety of Ru catalysts and reaction temperatures are suitable for the chain–walking reaction of methyl eugenol 1 to methyl isoeugenol 2.
From: Parts–per–million of ruthenium catalyze the selective chain–walking reaction of terminal alkenes
a Kinetics for the isomerization reaction of 1 g of 1 with Ru(methylallyl)2(COD) at three different reaction temperatures; error bars account for a 5% uncertaintity. b Isomerization reaction catalyzed by 0.001 mol% (10 ppm) of different commercially available Ru compounds, the Ru oxidation state for each compound is indicated. For entries 1–6, the reaction was carried out with 4–16 g of 1 adding the solid catalyst directly. For entries 7–12, the reaction was carried out with 0.3–1 g of 1 adding a solution of the catalyst in dichloromethane. Below, structures of the different Ru complexes employed as initial Ru source.
