Fig. 2: 2 + 2 Imine-olefin photocycloaddition reaction scope.
From: Intermolecular 2+2 imine-olefin photocycloadditions enabled by Cu(I)-alkene MLCT
Summary of imine and alkene substrate variation. All reactions carried out with 1 equiv alkene, 1.1 equiv imine, 20 mol % TpCu, in diethyl ether (0.15 M) and irradiated with a 100 W Hg lamp in borosilicate tubes; all yields are of isolated material following purification via basic alumina chromatography and diastereomeric ratios were determined via gas chromatography of crude reaction mixtures; all products detected as >95:5 exo:endo diastereomers. Yield in parentheses obtained in the absence of TpCu. a3 equiv of imine used.
