Fig. 4: Functional properties of PCP-Mn-DTA@GOx@1-MT nanosystem. | Nature Communications

Fig. 4: Functional properties of PCP-Mn-DTA@GOx@1-MT nanosystem.

From: Multifunctional metal-organic framework-based nanoreactor for starvation/oxidation improved indoleamine 2,3-dioxygenase-blockade tumor immunotherapy

Fig. 4

a Cumulative release of GOx from PCP-Mn-DTA@GOx@1-MT after treatments with different concentrations of H2O2 or H2O2 plus glucose (abbreviated as Glu). b, c pH values and generated H2O2 concentrations at various time points arisen from GOx (b) and PCP-Mn-DTA@GOx@1-MT (c) catalyzed disintegration reaction of glucose. d CLSM images and (e) quantitative measurements of intracellular ROS. Data represent mean ± SD (n = 4 independent samples). P-values were determined by unpaired Student’s t-test (two-tailed), **p < 0.01. Scale bar: 50 μm.

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