Fig. 1: Design of in vivo gene amplification.
From: An in vivo gene amplification system for high level expression in Saccharomyces cerevisiae
a Natural genome structures at the ribosomal DNA (rDNA) locus on chromosome XII and the CUP1 locus on chromosome VII. b Construct design for in vivo gene amplification (HapAmp). ARS autonomous replicating sequence.
