Fig. 5: Sox2 overexpression impairs intestinal identity in adult homeostasis. | Nature Communications

Fig. 5: Sox2 overexpression impairs intestinal identity in adult homeostasis.

From: Single-cell chromatin profiling of the primitive gut tube reveals regulatory dynamics underlying lineage fate decisions

Fig. 5

a–d Immunofluorescence images of Villin+/+;R26Sox2-IRES-GFP + (n = 3, left) and VillinCreERT2/+;R26Sox2-IRES-GFP (n = 4, right) for a SOX2 (red) and GFP (green), b CDX2 (red) and GFP (green), c Lysozyme C (LYZ, red) and GFP (green), and d OLFM4 (red) and GFP (green). Scale bars of a–d are 100 µm for top panels and 50 µm for bottom panels. White dotted boxes indicate areas of GFP expression.

Back to article page