Fig. 1: Fungal exposure increases with age. | Nature Communications

Fig. 1: Fungal exposure increases with age.

From: Temporal changes in gastrointestinal fungi and the risk of autoimmunity during early childhood: the TEDDY study

Fig. 1

a Abundance of fungal reads in TEDDY metagenomic samples (n = 12,262 from 888 children; median 2.6 × 107 total reads/sample). Curves show LOESS fit for samples from Finland (blue; n = 2855 from 238 children), Sweden (yellow; n =  4360 from 302 children), Germany (red; n = 1228 from 86 children), and USA (green; n = 3819 from 262 children). Shaded regions represent 95% confidence intervals. b The fungal percent of metagenomic reads in young children (TEDDY, 3–14 m, n = 6547), older children (TEDDY, 15 48 m, n = 5621), USA adults (HMP, n = 203), and non-Western adults from Fiji, Madagascar, Peru, and Tanzania (n = 315). Displayed are the interquartile range (IQR; boxes), median (line), and 1.5 IQR (whiskers). TEDDY countries left to right are Finland (blue; n = 2835 from 238 children), Sweden (yellow; n = 4331 from 302 children), Germany (red; n = 1220 from 86 children), and USA (green; n = 3784 from 262 children). Samples with zero fungal reads are shown having one read to allow logarithmic scaling. The P values were calculated by Kruskal–Wallis rank-sum tests. Source data are provided in the Source Data file.

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