Fig. 4: STORM imaging of transmembrane proteins or membrane-bound signaling proteins associated with the MPS.
From: Proteomic and functional analyses of the periodic membrane skeleton in neurons
a Left: 3D STORM images of two potassium channel subunits, Kv 1.2 and Kv 1.3, in axons. Middle: 1D autocorrelation of the imaged proteins for the axon region indicated by the dashed line in the left panels. Right: Average 1D autocorrelation of the imaged proteins over 20–90 randomly chosen axon regions. b Same as (a) but for five cell adhesion molecules, including neurofascin, NrCAM, L1CAM, NCAM1 and CHL1. c Same as (a) but for three membrane-associated (non-transmembrane) signaling molecules, including calcium/calmodulin-dependent protein kinase type IIβ (CAMK IIβ), heterotrimeric G protein β-subunit 1, and brain acid soluble protein 1, as well as a transmembrane signaling molecule, glycoprotein M6A. STORM images in a–c are representative examples from three independent experiments with similar results. Scale bars: 1 μm. Source data are provided as a Source Data file.
