Fig. 7: Ex vivo biodistribution and in vivo PA imaging.

A Ex vivo tissue distribution of RuDA-NPs in mice determined by the content of Ru (% injected dose (ID) of Ru per gram of tissues) at different post injection time. The data represent the mean ± SD (n = 3). Unpaired, two-sided t tests *p < 0.05, **p < 0.01, and ***p < 0.001. B In vivo PA images of tumor sites under excitation at 808 nm after intravenous injection of RuDA-NPs (10 μmol kg−1) at different time points. C Ru excreted out of the mice body via urine and feces after intravenous administration of RuDA-NPs (10 μmol kg−1) at different time intervals. The data represent the mean ± SD (n = 3).