Fig. 2: The genetic basis for bifurcated biosynthesis of desotamide and wollamide by Streptomyces. sp. MST-110588.
From: Bifurcation drives the evolution of assembly-line biosynthesis
a The architecture of the desotamide producing dsa BGC from Streptomyces scopuliridis SCSIO ZJ4625. b The architecture of the wollamide and desotamide producing wol BGC from Streptomyces sp. MST110588. c The proposed biosynthetic pathway of the wollamides and desotamides. The first three condensations are catalysed by WolI and WolH. The final two condensations are catalysed by WolG1 to produce desotamides or WolG2 to produce wollamides.
