Fig. 3: Heterologous production of the wollamides by overexpression of wolG2.
From: Bifurcation drives the evolution of assembly-line biosynthesis
a The extracted ion chromatograms (EIC) for masses corresponding to desotamide A ([M + H] = 697.40) and wollamide A ([M + H] = 754.46) from wild-type Streptomyces sp. MST-110588 producing both compounds. b The EICs of desotamide A and wollamide A from Streptomyces sp. MST-70754 producing desotamide A only. c The EICs of desotamide A and wollamide A from Streptomycessp. MST-70754/pBO1-wolG2 producing both compounds. Schematic representations of the assembly lines and overexpressed genes are also shown. (dsa desotamide, wol wollamide).
